Recombinant Human IL-7 Protein

重组人IL-7蛋白 | 重组人白细胞介素-7蛋白 | 重组人白介素-7蛋白

IL7 | IL-7 | IL-7interleukin-7 | interleukin 7 | Lymphopoietin-1 | PBGF

rp155999-10μg

10μg

无载体

≥95%(SDS-PAGE)

IL7, also known as interleukin 7, is a hematopoietic growth factor that belongs to the IL-7/IL-9 family. It is secreted by stromal cells in the bone marrow and thymus. IL7 stimulates the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. IL7 and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. It is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRß) during early T cell development. IL7 can be produced locally by intestinal epithelial and epithelial goblet cells and may serve as a regulatory factor for intestinal mucosal lymphocytes.

Measured in a cell proliferation assay using PHA-activated human peripheral blood lymphocytes (PBL). The ED50 for this effect is 0.12 ng/mL.

重组表达

17.4 kDa

No tag

17.0 kDa, under reducing conditions; 17.0 kDa, under non-reducing conditions.

E. coli Accession #: P13232 | E. coli

<1.0 EU/μg

人(Human)

26-177 aa

GDCDIEGKDGKQYESVLMVSIDQLLDSMKEIGSNCLNNEFNFFKRHICDANKEGMFLFRAARKLRQFLKMNSTGDFDLHLLKVSEGTTILLNCTGQVKGRKPAALGEAQPTKSLEENKSLKEQKKLNDLCFLKRLLQEIKTCWNKILMGTKEH

No

Yes