Recombinant Human Aurora B Protein

重组人Aurora B/AIM1蛋白 | 重组人 Aurora B 蛋白

AIK2AIM-1 | AIM1 | ARK-2 | ARK2 | AurB | AURKB | AURKB_HUMAN | Aurora 1 | Aurora and Ipl1 like midbody associated protein 1 | Aurora kinase B | Aurora related kinase 2 | Aurora- and Ipl1-like midbody-associated protein 1 | Aurora-B | Aurora-related kinase

rp156680-50μg

50μg

无载体

≥90%(SDS-PAGE)

Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Aurora-B, previously known as AIM-1, is a conserved eukaryotic mitotic protein kinase. In mammals, this kinase plays an essential role in chromosomal segregation processes, including chromosome condensation, alignment, control of spindle checkpoints, chromosome segregation, and cytokinesis. Aurora-B is overexpressed in various cancer cells, suggesting that the kinase activity perturbs chromosomal segregation processes. Its forced overexpression induces chromosomal number instability and progressive tumorigenicity in rodent cells in vitro and in vivo.

重组表达

40.3 kDa

N-His

41.8 kDa, reducing conditions

E. coli Accession #: Q96GD4 | E. coli

<1.0 EU/μg

人(Human)

1-344 aa

MGHHHHHHMAQKENSYPWPYGRQTAPSGLSTLPQRVLRKEPVTPSALVLMSRSNVQPTAAPGQKVMENSSGTPDILTRHFTIDDFEIGRPLGKGKFGNVYLAREKKSHFIVALKVLFKSQIEKEGVEHQLRREIEIQAHLHHPNILRLYNYFYDRRRIYLILEYAPRGELYKELQKSCTFDEQRTATIMEELADALMYCHGKKVIHRDIKPENLLLGLKGELKIADFGWSVHAPSLRRKTMCGTLDYLPPEMIEGRMHNEKVDLWCIGVLCYELLVGNPPFESASHNETYRRIVKVDLKFPASVPMGAQDLISKLLRHNPSERLPLAQVSAHPWVRANSRRVLPPSALQSVA

No

Yes