Recombinant Human Thrombopoietin GMP Protein

血小板生成素(TPO)重组蛋白 | 重组人血小板生成素GMP蛋白

Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating factor | MGDF | MGDFC-mpl ligand | MKCSF | MK-CSF | ML | MPL ligand | MPLLG | MGC163194 | Myeloproliferative leukemia virus oncogene ligand |

rp167459-GMP-50μg

50μg

无动物源

≥95%(SDS-PAGE&SEC-HPLC)

细胞系特异性细胞因子，影响巨核细胞从其固定的祖细胞增殖和成熟。它在巨核细胞发育的后期发挥作用。它可能是循环血小板的主要生理调节因子。

Measured in a cell proliferation assay using MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.05-0.5 ng/mL. The specific activity of Recombinant Human Thrombopoietin is >1 x 10^7 units/mg, which is calibrated against the human Thrombopoietin reference standard (NIBSC code: 03/124).

重组表达

18.7 kDa

No tag

19 kDa, under reducing conditions

E. coli Accession #: NP_000451.1 | E. coli

<0.1 EU/μg

人(Human)

22-195 aa

SPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNEL

Yes

Yes

Ala-Ser22-Pro-Ala-Pro-Pro-Ala-(Cys)-Asp-Leu