Recombinant Human IGF-II R/IGF2R Protein

胰岛素样生长因子2受体(IGF2R)重组蛋白

300 kDa mannose 6-phosphate receptor | cation-independent mannose-6 phosphate receptor | cation-independent mannose-6-phosphate receptor | CD222 antigen | CD222 | CI Man-6-P receptor | CIMPR | CI-MPR | IGF2R | IGF-II R | IGF-II receptor | IGFIIR | IGF-IIR

rp167530-10μg

10μg

无动物源

≥95%(SDS-PAGE)

≥95% (SDS-PAGE)

Purity ≥95% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function IGF2R is a multifunctional receptor with binding sites for a variety of ligands, including insulin-like growth factor II (IGF2; 147470), retinoic acid (RA), TGF-β (TGFB1; 190180), urokinase-type plasminogen activator receptor (UPAR, or PLAUR; 173391) and mannose 6-phosphate (M6P), a modification characteristic of a lysosomal enzyme. IGF2R plays a major role in controlling IGF signaling by directing IGF2 to lysosomes, targeting lysosomal enzymes to lysosomes, and recycling lysosomal enzymes from the plasma membrane

When Recombinant Human IGF-II R/IGF2R is immobilized at 2 μg/mL (100 µL/well), the concentration of Recombinant Human CREG Recombinant Human CREG that produces 50% of the optimal binding response is found to be approximately 2‑10 ng/mL.

重组表达

147 kDa

C-His

160-180 kDa, under reducing conditions

HEK293 Accession #: P11717 | HEK293

<0.1 EU/μg

人(Human)

43-1365 aa

APFPELCSYTWEAVDTKNNVLYKINICGSVDIVQCGPSSAVCMHDLKTRTYHSVGDSVLRSATRSLLEFNTTVSCDQQGTNHRVQSSIAFLCGKTLGTPEFVTATECVHYFEWRTTAACKKDIFKANKEVPCYVFDEELRKHDLNPLIKLSGAYLVDDSDPDTSLFINVCRDIDTLRDPGSQLRACPPGTAACLVRGHQAFDVGQPRDGLKLVRKDRLVLSYVREEAGKLDFCDGHSPAVTITFVCPSERREGTIPKLTAKSNCRYEIEWITEYACHRDYLESKTCSLSGEQQDVSIDLTPLAQSGGSSYISDGKEYLFYLNVCGETEIQFCNKKQAAVCQVKKSDTSQVKAAGRYHNQTLRYSDGDLTLIYFGGDECSSGFQRMSVINFECNKTAGNDGKGTPVFTGEVDCTYFFTWDTEYACVKEKEDLLCGATDGKKRYDLSALVRHAEPEQNWEAVDGSQTETEKKHFFINICHRVLQEGKARGCPEDAAVCAVDKNGSKNLGKFISSPMKEKGNIQLSYSDGDDCGHGKKIKTNITLVCKPGDLESAPVLRTSGEGGCFYEFEWHTAAACVLSKTEGENCTVFDSQAGFSFDLSPLTKKNGAYKVETKKYDFYINVCGPVSVSPCQPDSGACQVAKSDEKTWNLGLSNAKLSYYDGMIQLNYRGGTPYNNERHTPRATLITFLCDRDAGVGFPEYQEEDNSTYNFRWYTSYACPEEPLECVVTDPSTLEQYDLSSLAKSEGGLGGNWYAMDNSGEHVTWRKYYINVCRPLNPVPGCNRYASACQMKYEKDQGSFTEVVSISNLGMAKTGPVVEDSGSLLLEYVNGSACTTSDGRQTTYTTRIHLVCSRGRLNSHPIFSLNWECVVSFLWNTEAACPIQTTTDTDQACSIRDPNSGFVFNLNPLNSSQGYNVSGIGKIFMFNVCGTMPVCGTILGKPASGCEAETQTEELKNWKPARPVGIEKSLQLSTEGFITLTYKGPLSAKGTADAFIVRFVCNDDVYSGPLKFLHQDIDSGQGIRNTYFEFETALACVPSPVDCQVTDLAGNEYDLTGLSTVRKPWTAVDTSVDGRKRTFYLSVCNPLPYIPGCQGSAVGSCLVSEGNSWNLGVVQMSPQAAANGSLSIMYVNGDKCGNQRFSTRITFECAQISGSPAFQLQDGCEYVFIWRTVEACPVVRVEGDNCEVKDPRHGNLYDLKPLGLNDTIVSAGEYTYYFRVCGKLSSDVCPTSDKSKVVSSCQEKREPQGFHKVAGLLTQKLTYENGLLKMNFTGGDTCHKVYQRSTAIFFYCDRGTQRPVFLKETSDCSYLFEWRTQYACPPFDHHHHHH

Yes

Yes