Recombinant Human/Mouse/Rat Activin A GMP Protein

重组人/小鼠/大鼠激活素 A GMP 蛋白 | 重组人/小鼠/大鼠Activin A蛋白 | 重组人/小鼠/大鼠抑制素βA蛋白 | 重组人抑制素βA蛋白 | 重组小鼠抑制素βA蛋白 | 重组大鼠抑制素βA蛋白

Activin A | activin AB alpha polypeptide | Activin beta-A chain | erythroid differentiation factor | Erythroid differentiation protein | follicle-stimulating hormone-releasing protein | FSH-releasing protein | inhibin beta A chain | inhibin beta A subunit

rp168392-GMP-10μg

10μg

无动物源

≥97%(SDS-PAGE&SEC-HPLC)

抑制素和激活素分别抑制和激活垂体分泌促性腺激素。抑制素/激活素根据其亚基组成的不同，参与调节多种功能，如下丘脑和垂体激素分泌、性腺激素分泌、生殖细胞发育和成熟、红细胞分化、胰岛素分泌、神经细胞存活、胚胎轴发育或骨骼生长。抑制素似乎与激活素的功能相反。

Measured by its ability to induce hemoglobin expression in K562 human chronic myelogenous leukemia cells. The ED50for this effect is 0.2-1.2 ng/mL.The specific activity of Recombinant Human/Mouse/Rat Activin A is >1000 units/mg, which is calibrated against the human Activin A WHO reference standard (NIBSC code: 91/626).

重组表达

13 kDa (monomer)

No tag

14 kDa, reducing conditions. 24 kDa, non-reducing conditions.

CHO Accession #: P08476 | CHO

<0.01 EU/μg

人(Human)

311-426 aa

GLECDGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRGHSPFANLKSCCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS

Yes

Yes

Gly311-Leu-Glu-(Cys)-Asp-Gly-Lys-Val-Asn-Ile