Recombinant Human TGF-beta 1 GMP Protein

重组人转化生长因子β1蛋白 | 重组人类 TGF-β1 GMP 蛋白

CED | LAP | DPD1 | latency-associated peptide | TGF beta | TGF beta1 | TGFB | TGFB1 | TGF-beta 1 protein | TGFbeta 1 | TGF-beta 1 | TGFbeta | TGF-beta-1 | transforming growth factor beta-1 | transforming growth factor, beta 1 | IBDIMDE

rp168406-GMP-10μg

10μg

无动物源

≥97%(SDS-PAGE&SEC-HPLC)

TGFB1 是一种多功能蛋白质，可控制多种类型细胞的增殖、分化和其他功能。许多细胞都能合成 TGFB1，并有其特异性受体。它对许多其他生长因子具有正向和负向调节作用。它在骨重塑过程中发挥着重要作用，因为它是成骨细胞骨形成的强效刺激物，可引起成骨细胞的趋化、增殖和分化。

Measured by its ability to inhibit the IL-4-dependent proliferation of HT‑2 mouse T cells. The ED50 for this effect is 0.04-0.2 ng/mL.The specific activity of recombinant human TGF-β1 GMP is >1.0 x 10^7 units/mg, which is calibrated against the human TGF‑β1 Standard (NIBSC code: 89/514).

重组表达

12.8 kDa (monomer)

No tag

12 kDa, under reducing conditions. 24 kDa, under non-reducing conditions.

CHO Accession #: P01137.2 | CHO

<0.1 EU/μg

人(Human)

279-390 aa

ALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS

Yes

Yes

Ala-Leu-Asp-Thr-Asn-Tyr-(Cys)-Phe-Ser-Ser