Recombinant Mouse Fas Ligand/TNFSF6 Protein

凋亡相关因子配体(FASL)重组蛋白

apoptosis (APO-1) antigen ligand 1 | Apoptosis antigen ligand | APT1LG1 | APTL | CD178 antigen | CD178 | CD95L | CD95-L | Fas antigen ligand | Fas ligand (TNF superfamily, member 6) | Fas Ligand | FASLCD95 ligand | FASLG | TNFSF6 | TNFSF6FasL | tumor necr

rp168737-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Function Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Immobilized Human Fas/CD95 hFcat 2 μg/mL (100 μL/well) can bind Human Fas Ligand His, the EC50 of Human Fas Ligand His is 40-200 ng/mL.

重组表达

21.4 kDa

N-His

40-55 kDa, under reducing conditions

HEK293 Accession #: P41047 | HEK293

<0.1 EU/μg

小鼠(Mouse)

101-279 aa

HHHHHHQLFHLQKELAELREFTNQSLKVSSFEKQIANPSTPSEKKEPRSVAHLTGNPHSRSIPLEWEDTYGTALISGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNQPLNHKVYMRNSKYPEDLVLMEEKRLNYCTTGQIWAHSSYLGAVFNLTSADHLYVNISQLSLINFEESKTFFGLYKL

Yes

Yes