Recombinant Human AFP Protein

重组人AFP蛋白 | 重组人AFP蛋白

Alpha-1-fetoprotein | Alpha-fetoglobulin | Alpha-fetoprotein | Hereditary persistence of alpha fetoprotein | Alpha fetoprotein precursor | alpha-fetoprotein, Hereditary persistence of, included | AFP | HPAFP

rp169544-1mg

1mg

无动物源

≥90%(SDS-PAGE)

Purity: ≥90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin, AFP, vitamin D (Gc) protein, and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moiety. AFP is one of the several embryo-specific proteins and is a dominant serum protein as early in human embryonic life as one month, when albumin and transferrin are present in relatively small amounts. It is first synthesized in the human by the yolk sac and liver(1-2 months) and subsequently predominantly in the liver. A small amount of AFP is produced by the GI tract of the human conceptus. It has been proved that AFP may reappear in the serum in elevated amounts in adult life in association with normal restorative processes and with malignant growth. Alpha-fetoprotein (AFP) is a specific marker for hepatocellular carcinoma (HCC), teratoblastomas, and neural tube defect (NTD).

Immobilized Recombinant Human AFP Protein (rp169544) at 1.0 μg/mL can bind AFP Mouse mAb (Ab007318) with the EC50 of 41.5 ng/mL.​

重组表达

67.3 kDa

C-His

67.5 kDa, under reducing conditions; 57.0 kDa, under non-reducing conditions

HEK293 Accession #: P02771 | HEK293

<1.0 EU/μg

人(Human)

1-609 aa

MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAALGVHHHHHH

Yes

Yes