Recombinant Human Kallikrein 3/PSA Protein

重组人前列腺特异性抗原/激肽释放酶-3 | 重组人Kallikrein 3/PSA蛋白 | 重组人激肽释放酶 3/PSA 蛋白

EC 3.4.21.77 | Gamma-seminoprotein | Kallikrein-3 | P-30 antigen | PSA | Semenogelase | Seminin | APS seminin | EC 3.4.21 | EC 3.4.21.77 | Gamma-seminoprotein | hK3 | Kallikrein 3 | kallikrein 3, (prostate specific antigen) | Kallikrein-3 | kallikrein-rel

rp169548-1mg

1mg

无动物源

≥95%(SDS-PAGE)

>95% (SDS-PAGE)

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases. KLK3 contains one peptidase S1 domain. KLK3 is a glycoprotein produced almost exclusively by the prostate gland. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers.

Measured by its binding ability in a functional ELISA. Immobilized human Kallikrein 3/PSA (rp169548) at 1 μg/mL can bind PSA Mouse mAb (Ab005494) with the EC50 of 78.61 ng/mL.

重组表达

28.2 kDa

C-His

33.8 kDa, under reducing conditions; 30.3 kDa, under non-reducing conditions

HEK293 Accession #: P07288 | HEK293

<1.0 EU/μg

人(Human)

18-261 aa

APLILSRIVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPEDTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQEPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTGGKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVANPHHHHHHHHHH

Yes

Yes

Ala18