Recombinant Human Cofilin Protein

重组人cofilin蛋白 | 重组人类肌动蛋白丝切蛋白

CFL1 | Cofilin 1 | CFL | Cofilin 1 (Non-Muscle) | 18 KDa Phosphoprotein | Cofilin-1 | P18 | Epididymis Secretory Protein Li 15 | Cofilin | Non-Muscle Isoform | HEL-S-15 | 18 kDa phosphoprotein | Cofilin, non-muscle isoform | p18

rp169589-1mg

1mg

无载体

≥90%(SDS-PAGE)

>90%(SDS-PAGE)

Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: CFL1, also known as n-cofilin, is a member of the ADF/Cofilin family. This family comprises three genes: CFL1, CFL2 and DSTN (destrin). ADF/Cofilin family members bind G-actin monomers and depolymerize actin filaments through two mechanisms: severing and increasing the off-rate for actin monomers from the pointed end. Cofilin also binds with other proteins such as myosin, tropomyosin, α-actinin, gelsolin and scruin. These proteins compete with cofilin for actin binding. Сofilin also plays a role in innate immune response. CFL1 contains 1 ADF-H domain and is widely distributed in various tissues. It is important for normal progress through mitosis and normal cytokinesis.

重组表达

20.7 kDa

N-His

21.2 kDa, reducing conditions; 21.2 kDa, non-reducing conditions

E. coli Accession #: P23528 | E. coli

<1.0 EU/μg

人(Human)

1-166 aa

MGSSHHHHHHSSGLVPRGSHMASGVAVSDGVIKVFNDMKVRKSSTPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYALYDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQANCYEEVKDRCTLAEKLGGSAVISLEGKPL

No

Yes