Recombinant Human CCL7/MCP-3 Protein

重组人CCL7/MCP-3蛋白 | 重组人 CCL7/MCP-3 蛋白

C-C motif chemokine 7 | Ccl7 | CCL7_HUMAN | Chemokine CC motif ligand 7 | FIC | MARC | MCP-3 | Monocyte chemoattractant protein 3 | Monocyte chemotactic protein 3 | NC28 | SCYA6 | RP23-350G1.4 | SCYA7 | Small-inducible cytokine A7

rp169629-50μg

50μg

无载体

≥95%(SDS-PAGE)

Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining Description: MCP-2 and CCL7 are two monocyte chemotactic proteins produced by human MG-63 osteosarcoma cells. Both MCP-2 and CCL7 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP-1. CCL7 also shares 58% amino acid identity with MCP-2. CCL7 cDNA encodes a 99 amino acid residue precursor protein from which the N-terminal 23 amino acid residues are cleaved to generate the 76 amino acid residue mature CCL7. Mature CCL7 contains a potential N-linked and several possible O-linked glycosylation sites. Similarly to other C-C chemokines, all three MCP proteins are monocyte chemoattractants. In addition, the three MCPs can chemoattract activated NK cells as well as CD4+ and CD8+ T lymphocytes. All three cytokines have also been shown to attract eosinophils and induce histamine secretion from basophils.

Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/mL.

重组表达

9.0 kDa

No tag

11.8 kDa, under reducing condition；13.1 kDa, under non-reducing condition

E. coli Accession #: Q7Z7Q8 | E. coli

<1.0 EU/μg

人(Human)

34-109 aa

ENLYFQGQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL

No

Yes