Recombinant Human CD133 protein

重组人CD133蛋白 | 重组人Prominin-1蛋白 | 重组人prominin样蛋白1

AC133 | Antigen AC133 | CD133 | CORD12 | Hematopoietic stem cell antigen | hProminin | MCDR2 | MSTP061 | OTTHUMP00000217744 | OTTHUMP00000217745 | OTTHUMP00000217746 | PROM1 | PROM1_HUMAN | Prominin I | Prominin like 1 | Prominin like protein 1 precursor

rp169688-10μg

10μg

无载体

≥95%(SDS-PAGE)

May play a role in cell differentiation, proliferation and apoptosis (PubMed:24556617). Binds cholesterol in cholesterol-containing plasma membrane microdomains and may play a role in the organization of the apical plasma membrane in epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner (PubMed:20818439). Post-translational: Isoform 1 and isoform 2 are glycosylated. Acetylation at Lys-225, Lys-257 and Lys-264 by NAT8 and NAT8B may control PROM1 protein expression and its function in cell apoptosis.

Testing in progress

重组表达

11.1 kDa

N-His

11.6 kDa, under reducing conditions; 11.6 kDa, under non-reducing conditions.

E. coli Accession #: O43490 | E. coli

<1.0 EU/μg

人(Human)

20-108 aa

MHHHHHHGGQPSSTDAPKAWNYELPATNYETQDSHKAGPIGILFELVHIFLYVVQPRDFPEDTLRKFLQKAYESKIDYDKPETVILGLKIVYYEAG

No

Yes