Recombinant Human Cyclophilin B Protein

重组人Cyclophilin B蛋白 | 重组人Cyclophilin B蛋白 | 重组人类环丝氨酸蛋白酶B蛋白

Cyclophilin B | cyclophilin-like protein | CYPB | CYPBEC 5.2.1.8 | CYP-S1 | MGC2224 | OI9MGC14109 | peptidyl-prolyl cis-trans isomerase B | peptidylprolyl isomerase B (cyclophilin B) | PPIase B | PPIB | Rotamase B | S-cyclophilin | SCYLP | Cyclophilin B |

rp176704-1mg

1mg

无载体

≥95%(SDS-PAGE)

>95% SDS-PAGE

Purity: >95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Cyclophilin B (SCYLP, CyPB, and peptidyl-prolyl cis-trans isomerase B) is a 24 kDa glycoprotein member of the B subfamily of the cyclophilin-type PPIase family of molecules. It is both secreted and retained in the ER. When secreted, it mediates chemotaxis and T cell adhesion to fibronectin. This is likely due to its prolyl cis/trans isomerase activity. Intracellularly, Cyclophilin B appears to serve as a molecular chaperone for molecules destined for secretion. It does so via stabilization and facilitating the activity of additional chaperones. The human CyPB precursor is 216 amino acids (aa) in length. It contains a 25 aa signal sequence plus a 191 aa mature region. There is a partial heparin-binding sequence (aa 27‑34), a PPIase domain (aa 47‑204), and a C-terminal ER retention motif (aa 213‑216). Over aa 34‑216, the human and mouse sequences are 95% aa identical.

重组表达

22.5 kDa

N-His

22.6 kDa, reducing conditions; 22.6 and 45.6 kDa, non-reducing condition

E. coli Accession #: P23284 | E. coli

<1.0 EU/μg

人(Human)

34-216 aa

MGSSHHHHHHSSGLVPRGSHDEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE

No

Yes