Recombinant Human CD5 Protein

重组人CD5蛋白 | 重组人 CD5 蛋白

CD5 antigen | CD5 antigen (p56-62) | CD5 molecule | CD5 | LEU1T-cell surface glycoprotein CD5 | Lymphocyte antigen T1/Leu-1 | T1

rp176727-10μg

10μg

无动物源

≥95%(SDS-PAGE)

The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.

Immobilized Recombinant Human CD5 Protein (rp176727) at 1.0 μg/mL can bind CD5 Mouse mAb (Ab006673) with the EC50 of 11.62 ng/mL.

重组表达

42.3 kDa

C-His

51.9 kDa, under reducing conditions; 48.0 kDa, under non-reducing conditions

HEK293 Accession #: P06127 | HEK293

<1.0 EU/μg

人(Human)

1-372 aa

MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPHHHHHHHHHH

Yes

Yes