Recombinant Human CD79B Protein

重组人CD79B蛋白 | 重组人 CD79B 蛋白

B cell antigen receptor complex associated protein beta chain | B cell specific glycoprotein B29 | B-cell antigen receptor complex-associated protein beta chain | B-cell-specific glycoprotein B29 | B29 | B29/Ig-beta/CD79b | CD 79b | CD79b | CD79b antigen

rp176729-10μg

10μg

无动物源

≥90%(SDS-PAGE)

Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

1. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL. 2. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC50 of 51.95 ng/mL.

重组表达

16.0 kDa

C-His

26.8-38.0 kDa, under reducing conditions; 28.8-34.6 kDa, under non-reducing conditions

HEK293 Accession #: P40259 | HEK293

<1.0 EU/μg

人(Human)

1-159 aa

MARLALSPVPSHWMVALLLLLSAEPVPAARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNSASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNNTSEVYQGCGTELRVMGFSTLAQLKQRNTLKDHHHHHH

Yes

Yes

Ala29