Recombinant Human Galectin-3 Protein

重组人Galectin-3蛋白 | 重组人半乳凝集素-3蛋白

AGE-R3 | Carbohydrate-binding protein 35 | CBP 35,35 kDa lectin | CBP35 | GAL3 | Gal-3 | galactin-3 | Galactose-specific lectin 3 | Galactoside-binding protein | GALBPCBP35 | Galectin3 | Galectin-3 | GALIG | IgE-binding protein | L29 | L31 | L-31 | Lamini

rp179829-10μg

10μg

无载体

≥95%(SDS-PAGE)

LGALS3 (Galectin 3) is a Protein Coding gene. This gene encodes a member of the galectin family of carbohydrate-binding proteins. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. LGALS3 is a beta-galactoside-binding lectin and plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion, and T-cell regulation. LGALS3 has an important role in tumor progression through inhibition of apoptosis. LGALS3 expression is associated with neoplastic transformation and with differentiation of monocytes to macrophages. Elevated expression of LGALS3 has been demonstrated in the synovium of rheumatoid arthritis (RA). Diseases associated with LGALS3 include Follicular Adenoma and Papillary Carcinoma.

Measured by its ability to agglutinate human red blood cells. The ED50 for this effect is <5.0 µg/mL.

重组表达

26.0 kDa

No tag

29.0 kDa, under reducing conditions; 29.0 kDa, under non-reducing conditions.

E. coli Accession #: P17931 | E. coli

<1.0 EU/μg

人(Human)

2-250 aa

ADNFSLHDALSGSGNPNPQGWPGAWGNQPAGAGGYPGASYPGAYPGQAPPGAYPGQAPPGAYPGAPGAYPGAPAPGVYPGPPSGPGAYPSSGQPSATGAYPATGPYGAPAGPLIVPYNLPLPGGVVPRMLITILGTVKPNANRIALDFQRGNDVAFHFNPRFNENNRRVIVCNTKLDNNWGREERQSVFPFESGKPFKIQVLVEPDHFKVAVNDAHLLQYNHRVKKLNEISKLGISGDIDLTSASYTMI

No

Yes