Recombinant Human CCL24/Eotaxin-2/MPIF-2 Protein

重组人CCL24/Eotaxin-2/MPIF-2蛋白 | 重组人 CCL24/Eotaxin-2/MPIF-2 蛋白

chemokine (C-C motif) ligand 24 | CCL24 | Ckb-6 | Eosinophil chemotactic protein 2 | Eotaxin-2 | member 24 | MPIF2 | MPIF-2 | MPIF2Myeloid progenitor inhibitory factor 2 | MPIF-2Small-inducible cytokine A24 | SCYA24CK-beta-6

rp181317-10μg

10μg

无载体

≥95%(SDS-PAGE)

Protein Function:： CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with aspirin-exacerbated respiratory disease.

Testing in progress

重组表达

10.5 kDa

No tag

13.0 kDa, under reducing conditions; 25.0 kDa, under non-reducing conditions

E. coli Accession #: O00175 | E. coli

<1.0 EU/μg

人(Human)

27-119 aa

VVIPSPCCMFFVSKRIPENRVVSYQLSSRSTCLKGGVIFTTKKGQQFCGDPKQEWVQRYMKNLDAKQKKASPRARAVAVKGPVQRYPGNQTTC

No

Yes