Recombinant Human B3GAT1 Protein

重组人B3GAT1蛋白 | 重组人β-1,3-葡萄糖醛酸转移酶1蛋白

B3GAT1 | beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P) | Beta-1,3-glucuronyltransferase 1 | CD57 | EC 2.4.1.135 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 | GLCATP | GlcAT-P | GLCATPGLCUATP | GLCUATP | glcUAT-P |

rp183601-10μg

10μg

无动物源

≥95%(SDS-PAGE)

B3GAT1 is the key enzyme during the biosynthesis of the carbohydrate epitope HNK-1, which is present on a number of cell adhesion molecules important in neurodevelopment. Saturating concentrations of rVAR2 inhibited downstream integrin signaling, which was mimicked by knockdown of the core chondroitin sulfate synthesis enzymes β-1,3-glucuronyltransferase 1 (B3GAT1) and chondroitin sulfate N-acetylgalactosaminyltransferase 1 (CSGALNACT1). Post-translational: The soluble form derives from the membrane form by proteolytic processing.

Testing in progress

重组表达

36.2 kDa

N-His

44.3 kDa, under reducing conditions; 98.7 kDa, under non-reducing conditions.

HEK293 Accession #: Q9P2W7 | HEK293

<1.0 EU/μg

人(Human)

25-334 aa

METDTLLLWVLLLWVPGSTGHHHHHHHQSTLAPLLAVHKDEGSDPRRETPPGADPREYCTSDRDIVEVVRTEYVYTRPPPWSDTLPTIHVVTPTYSRPVQKAELTRMANTLLHVPNLHWLVVEDAPRRTPLTARLLRDTGLNYTHLHVETPRNYKLRGDARDPRIPRGTMQRNLALRWLRETFPRNSSQPGVVYFADDDNTYSLELFEEMRSTRRVSVWPVAFVGGLRYEAPRVNGAGKVVGWKTVFDPHRPFAIDMAGFAVNLRLILQRSQAYFKLRGVKGGYQESSLLRELVTLNDLEPKAANCTKILVWHTRTEKPVLVNEGKKGFTDPSVEI

Yes

Yes