Recombinant Human CXADR Protein

重组人CXADR蛋白 | 重组人 CXADR 蛋白

CAR4/6 | coxsackie virus and adenovirus receptor | coxsackie virus B receptor | coxsackievirus and adenovirus receptor | CVB3 binding protein | CVB3 BP | CVB3-binding protein | CXADR | HCAR | HCVADR | CAR10Coxsackievirus B-adenovirus receptor

rp183611-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Protein Function: CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.

Testing in progress

重组表达

24.8 kDa

C-His

29.0-34.0 kDa, under reducing conditions; 24.0-30.0 kDa, under non-reducing conditions

HEK293 Accession #: P78310 | HEK293

<1.0 EU/μg

人(Human)

1-237 aa

MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGHHHHHH

Yes

Yes