Recombinant Human Ephrin-A5 Protein

重组人Ephrin-A5蛋白 | 重组人肾上腺素A5蛋白 | 重组人肝配蛋白A5 | 重组人AL-1蛋白

AF1 | AL-1 | EFL-5 | EFNA5 | EPH-related receptor tyrosine kinase ligand 7 | EphrinA5 | Ephrin-A5 | EPLG7 | GLC1M | LERK-7 | LERK7EFL5 | RAGS

rp183615-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Ephrin-A5 also known as EFNA5, is a member of the Ephrin family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. Ephrin-A5/EFNA5 may function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Ephrin-A5/EFNA5 also serves as a cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.

Immobilized Recombinant Human Ephrin-A5 Protein (rp183615) at 1.0 μg/mL can bind Recombinant Human EphA4 Protein (rp183616) with the EC50 of 175.1 ng/mL.

重组表达

22.0 kDa

C-His

26.0 kDa, under reducing conditions; 25.1 kDa, under non-reducing conditions.

HEK293 Accession #: P52803 | HEK293

<1.0 EU/μg

人(Human)

1-203 aa

MLHVEMLTLVFLVLWMCVFSQDPGSKAVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCMKTIGVHDRVFDVNDKVENSLEPADDTVHESAEPSRGENHHHHHH​

Yes

Yes