Recombinant Human Guanylyl Cyclase C/GUCY2C Protein

重组人Guanylyl Cyclase C/GUCY2C蛋白 | 重组人Guanylyl Cyclase C/GUCY2C蛋白 | 重组人Guanylyl Cyclase C/GUCY2C蛋白 | 重组人鸟苷酸环化酶C/GUCY2C 蛋白

DIAR6 | EC 4.6.1 | GCC | GC-C | guanylate cyclase 2C (heat stable enterotoxin receptor) | Guanylate Cyclase C | Guanylyl Cyclase C | GUC2C | GUC2CEC 4.6.1.2 | GUCY2C | heat-stable enterotoxin receptor | hSTAR | Intestinal guanylate cyclase | MUCIL | STA R

rp183624-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Protein Function: Guanylyl cyclase that catalyzes synthesis of cyclic GMP (cGMP) from GTP (PubMed:11950846, PubMed:1718270, PubMed:22436048, PubMed:22521417, PubMed:23269669). Receptor for the E.coli heat-stable enterotoxin; E.coli enterotoxin markedly stimulates the accumulation of cGMP in mammalian cells expressing GUCY2C (PubMed:1680854, PubMed:1718270). Also activated by the endogenous peptides guanylin and uroguanylin (PubMed:8381596).

Testing in progress

重组表达

46.8 kDa

C-His

57.4-91.7 kDa, under reducing conditions; 57.4-91.7 & 180-250 kDa, under non-reducing conditions

HEK293 Accession #: P25092 | HEK293

<1.0 EU/μg

人(Human)

1-430 aa

MKTLLLDLALWSLLFQPGWLSFSSQVSQNCHNGSYEISVLMMGNSAFAEPLKNLEDAVNEGLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTCEGLDLLRKISNAQRMGCVLIGPSCTYSTFQMYLDTELSYPMISAGSFGLSCDYKETLTRLMSPARKLMYFLVNFWKTNDLPFKTYSWSTSYVYKNGTETEDCFWYLNALEASVSYFSHELGFKVVLRQDKEFQDILMDHNRKSNVIIMCGGPEFLYKLKGDRAVAEDIVIILVDLFNDQYFEDNVTAPDYMKNVLVLTLSPGNSLLNSSFSRNLSPTKRDFALAYLNGILLFGHMLKIFLENGENITTPKFAHAFRNLTFEGYDGPVTLDDWGDVDSTMVLLYTSVDTKKYKVLLTYDTHVNKTYPVDMSPTFTWKNSKLPNDITGRGPQHHHHHH

Yes

Yes