Recombinant Human S100A9 Protein

重组人S100A9蛋白 | 重组人S100A9蛋白

60B8AG | CAGB | Calgranulin B | Calgranulin-B | Calprotectin L1H subunit | CFAG | CGLB | Cystic fibrosis antigen B | L1AG | Leukocyte L1 complex heavy chain | LIAG | MAC387 | MIF | Migration inhibitory factor related protein 14 | Migration inhibitory fact

rp183637-10μg

10μg

无载体

≥95%(SDS-PAGE)

Protein Function: Calcium-binding protein. Has antimicrobial activity towards bacteria and fungi. Important for resistance to invasion by pathogenic bacteria. Up-regulates transcription of genes that are under the control of NF-kappa-B. Plays a role in the development of endotoxic shock in response to bacterial lipopolysaccharide (LPS) (By similarity). Promotes tubulin polymerization when unphosphorylated. Promotes phagocyte migration and infiltration of granulocytes at sites of wounding. Plays a role as a pro-inflammatory mediator in acute and chronic inflammation and up-regulates the release of IL8 and cell-surface expression of ICAM1. Extracellular calprotectin binds to target cells and promotes apoptosis. Antimicrobial and proapoptotic activity is inhibited by zinc ions.

1. Immobilized Recombinant Human S100A8 Protein (rp183594) at 2.0 μg/mL can bind Recombinant Human S100A9 Protein (rp183637) with the EC50 of 135.5 ng/mL. 2. Immobilized Recombinant Human S100A9 Protein (rp183637) at 2.0 μg/mL can bind Recombinant Human S100A8 Protein (rp183594) with the EC50 of 194.6 ng/mL.

重组表达

14.0 kDa

C-His

12.7 & 28.7 kDa, under reducing conditions; 12.7 & 28.7 kDa, under non-reducing conditions

E. coli Accession #: P06702 | E. coli

<1.0 EU/μg

人(Human)

1-114 aa

MTCKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKKENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMARLTWASHEKMHEGDEGPGHHHKPGLGEGTPHHHHHH

No

Yes