Recombinant Human Cystatin A Protein

重组人Cystatin A蛋白 | 重组人胱抑素A蛋白

CSTA | cystatin A (stefin A) | Cystatin A | cystatin AS | cystatin-A | Stefin A | STF1 | STF1Cystatin-AS | STFA | STFAStefin-A | AREI

rp183667-10μg

10μg

无载体

≥95%(SDS-PAGE)

Protein Function:： Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is located mainly in the keratohyaline granules of the stratum granulosum and the cornified envelope of the stratum corneum in the epidermis. The cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. Cystatins are physiological inhibitors of cysteine proteinases which are widely distributed in human tissues and fluids. Cystatins typically comprise about 115 amino acids, are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds. Cystatins may be glycosylated and / or phosphorylated, with similarity to fetuins, kininogens, stefins, histidine-rich glycoproteins and cystatin-related proteins. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired inhibitory activity. Cystatins mainly inhibit peptidases belonging to peptidase families C1 (papain family) and C13 (legumain family).

Testing in progress

重组表达

11.8 kDa

N-His

12.2 kDa, under reducing conditions; 12.2 kDa, under non-reducing conditions

E. coli Accession #: P01040 | E. coli

<1.0 EU/μg

人(Human)

2-98 aa

MHHHHHHIPGGLSEAKPATPEIQEIVDKVKPQLEEKTNETYGKLEAVQYKTQVVAGTNYYIKVRAGDNKYMHLKVFKSLPGQNEDLVLTGYQVDKNKDDELTGF

No

Yes