Recombinant Human Aminopeptidase N/CD13 Protein

重组人Aminopeptidase N/CD1蛋白 | 重组人氨基肽酶N蛋白 | 重组人分化簇13蛋白

alanyl (membrane) aminopeptidase | Alanyl aminopeptidase | Aminopeptidase M | Aminopeptidase N | ANPEP | AP-M | APN | AP-N | CD13 antigen | CD13 | CD13APN | EC 3.4.11 | EC 3.4.11.2 | gp150 | LAP1 | Microsomal aminopeptidase | Myeloid plasma membrane glyco

rp183728-10μg

10μg

无动物源

≥95%(SDS-PAGE)

The human ANPEP gene encodes aminopeptidase N (APN), which is also known as microsomal aminopeptiase, alanyl aminopeptidase, aminopeptidase M, CD13, or membrane protein p161. The deduced amino acid sequence of human APN consists of a short cytoplasmic tail (residues 2 to 8), a transmembrane region (residue 9 to 32), a Ser/Thr rich region and a zinc metalloprotease domain (residues 69 to 966). Widely expressed in many cells, tissues and species, APN cleaves the N-terminal amino acids from bioactive peptides, leading to their inactivation or degradation. The roles of APN in many fields, such as neuroscience, hematopoietic cells, immune system, angiogenesis, cancer and viral infection, have been reviewed. Post-translational: Sulfated. N- and O-glycosylated. May undergo proteolysis and give rise to a soluble form.

Immobilized Recombinant Human Aminopeptidase N/CD13 Protein (rp183728) at 1.0 μg/mL can bind Recombinant CD13 Antibody (Ab093779) with the EC50 of 10.7 ng/mL.

重组表达

104.1 kDa

C-10His

116.7-143.9 kDa, under reducing conditions; 112.4-136.7 kDa, under non-reducing conditions.

CHO Accession #: P15144 | CHO

<1.0 EU/μg

人(Human)

69-967 aa

KAWNRYRLPNTLKPDSYRVTLRPYLTPNDRGLYVFKGSSTVRFTCKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPDIDKTELVEPTEYLVVHLKGSLVKDSQYEMDSEFEGELADDLAGFYRSEYMEGNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNGVLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPKSDQIGLPDFNAGAMENWGLVTYRENSLLFDPLSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNRSIQLPTTVRDIMNRWTLQMGFPVITVDTSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGRQQQDYWLIDVRAQNDLFSTSGNEWVLLNLNVTGYYRVNYDEENWRKIQTQLQRDHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQYMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPNNNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNPDLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSKHHHHHHHHHH

Yes

Yes