Recombinant Human Caveolin-1 Protein

重组人Caveolin-1蛋白 | 重组人类 Caveolin-1 蛋白

CAV | CAV1 | caveolae protein, 22kD | caveolin 1, caveolae protein, 22kDa | Caveolin1 | Caveolin-1 | cell growth-inhibiting protein 32 | MSTP085 | VIP21

rp183730-1mg

1mg

无载体

≥95%(SDS-PAGE)

Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： Caveolin-1 is a palmitoylated 22 kDa membrane-associated protein in caveolae, the cholesterol-rich invaginations in the plasma membrane involved in vesicular transport and regulation of lipid rafts. Caveolin-1 expression is dysregulated during cancer progression and exhibits both positive and negative effects on tumor progression. The central region of Caveolin-1 (aa 105‑125) is buried in the lipid layer, while the N- and C-terminal flanking regions are exposed to the cytoplasm and interact with many other proteins. Within these cytoplasmic regions, human Caveolin-1 shares 95% aa sequence identity with mouse and rat Caveolin-1. Alternate splicing in human, mouse and rat generates an isoform with a deletion of the N-terminal 31 residues.

重组表达

8.9 kDa

No tag

13.0 kDa, under reducing conditions; 13.0 kDa, under non-reducing conditions

E. coli Accession #: Q03135 | E. coli

<1.0 EU/μg

人(Human)

2-80 aa

SGGKYVDSEGHLYTVPIREQGNIYKPNNKAMADELSEKQVYDAHTKEIDLVNRDPKHLNDDVVKIDFEDVIAEPEGTHS

No

Yes