Recombinant Human MAP1LC3A Protein

重组人MAP1LC3A蛋白 | 重组人 MAP1LC3A 蛋白

Autophagy related protein LC3 A | ATG8E | Autophagy related ubiquitin like modifier LC3 A | Autophagy-related protein LC3 A | Autophagy-related ubiquitin-like modifier LC3 A | LC3 | LC3A | MAP1 light chain 3 like protein 1 | MAP1 light chain 3-like protei

rp183742-10μg

10μg

无载体

≥95%(SDS-PAGE)

Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed:31006537, PubMed:31006538).

Testing in progress

重组表达

15.1 kDa

C-His

13.1 kDa, under reducing conditions; 13.1 & 30.6 kDa, under non-reducing conditions

E. coli Accession #: Q9H492 | E. coli

<1.0 EU/μg

人(Human)

1-121 aa

MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFGFHHHHHH

No

Yes