Recombinant Human CD90/Thy1 Protein

Thy1 | 重组人CD90/Thy1蛋白 | 重组人 CD90/Thy1 蛋白

CD90 antigen | CD90 | CDw90 | FLJ33325 | Thy-1 antigen | Thy-1 cell surface antigen | thy-1 membrane glycoprotein | Thy-1 T-cell antigen | Thy1 | CD7 antibody | CD90 antibody | CD90 antigen antibody | CDw90 antibody | FLJ33325 antibody | MGC128895 antibod

rp183754-50μg

50μg

无动物源

≥95%(SDS-PAGE)

Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining Description: CD90, also known as Thy1, is an approximately 25-35 kDa glycoprotein that mediates cellular adhesion and exerts wide-ranging effects in different tissues. CD90 is expressed on hematopoietic progenitor cells, neurons, and activated vascular endothelial cells. Its species-specific expression in lymphoid cells allows its use as a thymocyte and pan T cell marker in mice but not in humans. CD90 can form dimers and higher-order multimers. It binds to heparin, the proteoglycan Syndecan-4, and Integrins alpha M beta 2, alpha V beta 3, and alpha V beta 5. Through these interactions, CD90 inhibits neurite outgrowth, promotes astrocyte adhesion, mediates the adhesion and extravasation of leukocytes and melanoma cells, supports Thrombospondin-1-induced disassembly of fibroblast focal adhesions, and inhibits the activation of latent TGF-beta 1, myofibroblast differentiation, and lung fibrosis. Human Thy-1 shares 63% and 66% amino acid similarity with mouse and rat homologs.

Immobilized Recombinant Human CD90/Thy1 Protein (rp183754) at 2.0 μg/mL can bind CD90/Thy1 Mouse mAb (Ab095497) with the EC50 of 287.4 ng/mL.​

重组表达

13.4 kDa

C-His

16.8-33.2 kDa, under reducing condition; 16.8-33.2 kDa, under non-reducing condition

HEK293 Accession #: P04216 | HEK293

<1.0 EU/μg

人(Human)

1-130 aa

MNLAISIALLLTVLQVSRGQKVTSLTACLVDQSLRLDCRHENTSSSPIQYEFSLTRETKKHVLFGTVGVPEHTYRSRTNFTSKYNMKVLYLSAFTSKDEGTYTCALHHSGHSPPISSQNVTVLRDKLVKCHHHHHH

Yes

Yes