Recombinant Human NLRP3 Protein

重组人NLRP3蛋白 | 重组人类 NLRP3 蛋白

AII/AVP | Angiotensin/vasopressin receptor AII/AVP like | Angiotensin/vasopressin receptor AII/AVP-like | C1orf7 | Caterpiller protein | CIAS 1 | CIAS1 | CLR1.1 | Cold autoinflammatory syndrome 1 | Cold autoinflammatory syndrome 1 protein | Cryopyrin | Fa

rp183755-10μg

10μg

无载体

≥90%(SDS-PAGE)

Protein Function: May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA. Activates caspase-1 in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18.

重组表达

26.8 kDa

N-His

30.4 & 57.3 kDa, under reducing conditions; 28.8 & 55.0 kDa, under non-reducing conditions

E. coli Accession #: Q96P20 | E. coli

人(Human)

4-223 aa

MHHHHHHASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVV

No

Yes