Recombinant Human AMPK alpha 1 Protein

重组人AMPK alpha 1蛋白 | 重组人类 AMPK alpha 1 蛋白

5 AMP activated protein kinase alpha 1catalytic subunit | 5 AMP activated protein kinase catalytic alpha 1 chain | 5' AMP activated protein kinase catalytic subunit alpha 1 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | AAPK1 | AAPK1_HUMAN

rp184863-10μg

10μg

无载体

≥90%(SDS-PAGE)

Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit.

重组表达

24.9 kDa

N-His

28.8 & 54.8 kDa, under reducing conditions; 29.6 & 54.5 kDa, under non-reducing conditions

E. coli Accession #: Q13131 | E. coli

<1.0 EU/μg

人(Human)

349-559 aa

MHHHHHHKDFYLATSPPDSFLDDHHLTRPHPERVPFLVAETPRARHTLDELNPQKSKHQGVRKAKWHLGIRSQSRPNDIMAEVCRAIKQLDYEWKVVNPYYLRVRRKNPVTSTYSKMSLQLYQVDSRTYLLDFRSIDDEITEAKSGTATPQRSGSVSNYRSCQRSDSDAEAQGKSSEVSLTSSVTSLDSSPVDLTPRPGSHTIEFFEMCANLIKILAQ

No

Yes