Recombinant Human Livin Protein

重组人Livin蛋白

baculoviral IAP repeat containing 7 | baculoviral IAP repeat-containing 7 | BIRC7 | KIAP | KIAPRING finger protein 50 | Kidney inhibitor of apoptosis protein | livin inhibitor-of-apoptosis | Livin | Melanoma inhibitor of apoptosis protein | ML-IAP | MLIAP

rp184877-10μg

10μg

无载体

≥90%(SDS-PAGE)

BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy. Post-translational: Autoubiquitinated and undergoes proteasome-mediated degradation. The truncated protein (tLivin) not only loses its anti-apoptotic effect but also acquires a pro-apoptotic effect.

Testing in progress

重组表达

33.6 kDa

C-His

37.4 kDa, under reducing conditions; 37.4 kDa, under non-reducing conditions.

E. coli Accession #: Q96CA5 | E. coli

<1.0 EU/μg

人(Human)

1-298 aa

MGPKDSAKCLHRGPQPSHWAAGDGPTQERCGPRSLGSPVLGLDTCRAWDHVDGQILGQLRPLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSVPASGYPELPTPRREVQSESAQEPGGVSPAEAQRAWWVLEPPGARDVEAQLRRLQEERTCKVCLDRAVSIVFVPCGHLVCAECAPGLQLCPICRAPVRSRVRTFLSHHHHHH

No

Yes