Recombinant Human FGF-12 Protein

重组人FGF12蛋白 | 重组人成纤维细胞生长因子12蛋白

FGF12 | FGF-12 | FGF12B | FHF1 | FHF-1 | FHF1Fibroblast growth factor homologous factor 1 | fibroblast growth factor 12 | fibroblast growth factor 12B | fibroblast growth factor FGF-12b | Myocyte-activating factor

rp184901-10μg

10μg

无载体

≥95%(SDS-PAGE)

FGF12 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF12 lacks the N-terminal signal sequence present in most of the FGF family members, but it contains clusters of basic residues that have been demonstrated to act as a nuclear localization signal. When transfected into mammalian cells, FGF12 accumulated in the nucleus, but was not secreted. The specific function of FGF12 gene has not yet been determined. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.

Immobilized Recombinant Human FGFR4 Protein (rp146021) at 1.0 μg/mL can bind Recombinant Human FGF12 Protein (rp184901) with the EC50 of 179.7 ng/mL.​

重组表达

20.3 kDa

No tag

18.1 kDa, under reducing conditions; 18.0 & 37.9 kDa, under non-reducing conditions.

E. coli Accession #: P61328-2 | E. coli

<1.0 EU/μg

人(Human)

2-181 aa

ESKEPQLKGIVTRLFSQQGYFLQMHPDGTIDGTKDENSDYTLFNLIPVGLRVVAIQGVKASLYVAMNGEGYLYSSDVFTPECKFKESVFENYYVIYSSTLYRQQESGRAWFLGLNKEGQIMKGNRVKKTKPSSHFVPKPIEVCMYREQSLHEIGEKQGRSRKSSGTPTMNGGKVVNQDST

No

Yes