Recombinant Human SULT1A3 Protein

重组人SULT1A3蛋白 | 重组人磺基转移酶1A3蛋白

Cytosolic Sulfotransferase 1A3 | EC 2.8.2 | EC 2.8.2.1 | HAST | HAST3 | M form) phenol sulfotransferase | MGC117469 | Monoamine-sulfating phenol sulfotransferase | M-PST | ST1A3/ST1A4 | STM | sulfotransferase family | Sulfotransferase | SULT1A3 | Thermola

rp184939-10μg

10μg

无载体

≥95%(SDS-PAGE)

SULT1A3 belongs to the sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. They are different in their tissue distributions and substrate specificities while their gene structure (number and length of exons) is similar. SULT1A3 gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Four sulfotransferase genes are located on the p arm of chromosome 16; this gene and SULT1A4 arose from a segmental duplication. It is the most centromeric of the four sulfotransferase genes. Exons of this gene overlap with exons of a gene that encodes a protein containing GIY-YIG domains (GIYD1). SULT1A3 is expressed in liver, colon, kidney, lung, brain, spleen, small intestine, placenta and leukocyte. SULT1A3 is a sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of phenolic monoamines (neurotransmitters such as dopamine, norepinephrine and serotonin) and phenolic and catechol drugs. Post-translational: The N-terminus is blocked.

Testing in progress

重组表达

35.0 kDa

N-His

34.9 kDa, under reducing conditions; 34.9 kDa, under non-reducing conditions.

E. coli Accession #: P0DMM9 | E. coli

<1.0 EU/μg

人(Human)

2-295 aa

MHHHHHHELIQDTSRPPLEYVKGVPLIKYFAEALGPLQSFQARPDDLLINTYPKSGTTWVSQILDMIYQGGDLEKCNRAPIYVRVPFLEVNDPGEPSGLETLKDTPPPRLIKSHLPLALLPQTLLDQKVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWDSFLEKFMAGEVSYGSWYQHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVGRSLPEETMDFMVQHTSFKEMKKNPMTNYTTVPQELMDHSISPFMRKGMAGDWKTTFTVAQNERFDADYAEKMAGCSLSFRSEL

No

Yes