Recombinant Human Integrin beta 1 Protein

重组人Integrin beta 1蛋白 | 重组人整合素beta-1蛋白

beta1 integrin | CD_antigen=CD29 | CD29 | Fibronectin receptor subunit beta | FNRB | Glycoprotein IIa | GP IIa | GPIIA | Integrin beta-1 | Integrin subunit beta 1 | integrin VLA-4 beta subunit | Integrin | ITB1_HUMAN | ITGB1 | MDF2 | MSK12 | OTTHUMP000000

rp186545-10μg

10μg

无动物源

≥90%(SDS-PAGE)

ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct target of miR-493-5p suggesting that ITGB1 and miR-493-5p may have potential prognostic value and may be useful as tumor biomarkers for the diagnosis of NSCLC patients. Diseases associated with ITGB1 include Gallbladder Cancer and Breast Cancer.

Immobilized Recombinant Human Integrin beta 1 Protein (rp186545) at 1.0 μg/mL can bind OS2966 (anti-ITGB1) (Ab177919) with the EC50 of 36.5 ng/mL.

重组表达

84.4 kDa

C-Basic Tail & His

108.0-132.9 kDa, under reducing conditions; 103.1-124.2 & 143.8-250.0 kDa, under non-reducing conditions.

HEK293 Accession #: P05556 | HEK293

<1.0 EU/μg

人(Human)

1-728 aa

MNLQPIFWIGLISSVCCVFAQTDENRCLKANAKSCGECIQAGPNCGWCTNSTFLQEGMPTSARCDDLEALKKKGCPPDDIENPRGSKDIKKNKNVTNRSKGTAEKLKPEDITQIQPQQLVLRLRSGEPQTFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDFRIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTNKGEVFNELVGKQRISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQCHLENNMYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTLSANSSNVIQLIIDAYNSLSSEVILENGKLSEGVTISYKSYCKNGVNGTGENGRKCSNISIGDEVQFEISITSNKCPKKDSDSFKIRPLGFTEEVEVILQYICECECQSEGIPESPKCHEGNGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRKRDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCKCRVCECNPNYTGSACDCSLDTSTCEASNGQICNGRGICECGVCKCTDPKFQGQTCEMCQTCLGVCAEHKECVQCRAFNKGEKKDTCTQECSYFNITKVESRDKLPQPVQPDPVSHCKEKDVDDCWFYFTYSVNGNNEVMVHVVENPECPTGPD DTSGLENLYFQGGKNAQCKKKLQALKKKNAQLKWKLQALKKKLAQGGHHHHHH

Yes

Yes