Recombinant Human DCXR Protein

重组人DCXR蛋白 | 重组人 L-木糖醇还原酶

Carbonyl reductase 2 | Carbonyl reductase II | DCR | Dcxr | DCXR_HUMAN | Dicarbonyl and L xylulose reductase | Dicarbonyl L xylulose reductase | Dicarbonyl/ L xylulose reductase | Dicarbonyl/L-xylulose reductase | HCR2 | HCRII | Human carbonyl reductase 2

rp188239-10μg

10μg

无载体

≥95%(SDS-PAGE)

DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and distal sections of the corpus region. HCR2 is weakly or not expressed in brain, lung, heart, spleen and testis. DCXR catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. DCXR participates in the uronate cycle of glucose metabolism. It may play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

Testing in progress

重组表达

26.7 kDa

N-His

25.6 kDa, under reducing conditions; 25.1 & 50.4 kDa, under non-reducing conditions.

E. coli Accession #: Q7Z4W1 | E. coli

<1.0 EU/μg

人(Human)

2-244 aa

MHHHHHHELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGGFWAC

No

Yes