Recombinant Human ENPP-5 Protein

重组人ENPP-5蛋白 | 重组人外核苷酸焦磷酸酶/磷酸二酯酶家族成员5蛋白

EC 3.1 | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative function) | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) | ectonucleotide pyrophosphatase/phosphodiesterase family member 5 | E-NPP 5 | ENPP5 | ENPP-5 | KIAA0879 | NPP5

rp188314-10μg

10μg

无动物源

≥95%(SDS-PAGE)

Ectonucleotide pyrophosphatase/phosphodiesterase 5 (ENPP-5 or NPP5) belongs to a group of ecto-enzymes which regulate the availability of extracellular nucleotides. This enzyme family forms a subgroup of a larger family that also includes arylsulfatases, phosphopentomutases, 2,3-bisphosphoglycerate-independent phosphoglycerate mutases (iPGM), and alkaline phosphatases. Mature human ENPP-5 is an approximately 50 kDa protein that consists of a 407 amino acid (aa) extracellular region with one phosphodiesterase/nucleotide pyrophosphatase domain, a 21 aa transmembrane segment, and a 25 aa cytoplasmic tail. Within the ectodomain, human ENPP-5 shares 85% aa sequence identity with mouse and rat ENPP-5. R&D Systems in-house testing indicates that recombinant human ENPP-5 exhibits phosphodiesterase activity with the substrate O-(4-Nitrophenylphosphoryl) choline. Post-translational: N-glycosylated.

Measured by its ability to cleave O-(4-Nitrophenylphosphoryl) choline. The specific activity is >300 pmol/min/μg.

重组表达

47.6 kDa

C-His

58.4-74.6 kDa, under reducing conditions; 58.4-74.6 kDa, under non-reducing conditions.

HEK293 Accession #: Q9UJA9 | HEK293

<1.0 EU/μg

人(Human)

1-430 aa

MTSKFLLVSFILAALSLSTTFSLQPDQQKVLLVSFDGFRWDYLYKVPTPHFHYIMKYGVHVKQVTNVFITKTYPNHYTLVTGLFAENHGIVANDMFDPIRNKSFSLDHMNIYDSKFWEEATPIWITNQRAGHTSGAAMWPGTDVKIHKRFPTHYMPYNESVSFEDRVAKIIEWFTSKEPINLGLLYWEDPDDMGHHLGPDSPLMGPVISDIDKKLGYLIQMLKKAKLWNTLNLIITSDHGMTQCSEERLIELDQYLDKDHYTLIDQSPVAAILPKEGKFDEVYEALTHAHPNLTVYKKEDVPERWHYKYNSRIQPIIAVADEGWHILQNKSDDFLLGNHGYDNALADMHPIFLAHGPAFRKNFSKEAMNSTDLYPLLCHLLNITAMPHNGSFWNVQDLLNSAMPRVVPYTQSTILLPGSVKPAEYDQEGSHHHHHH

Yes

Yes