Recombinant Human XTP3TPA Protein

重组人XTP3TPA蛋白 | 重组人dCTP焦磷酸酶1蛋白

CDA03 | dCTP pyrophosphatase 1 | DCTP1_HUMAN | dCTPase 1 | DCTPP1 | Deoxycytidine triphosphatase 1 | Deoxycytidine-triphosphatase 1 | RS21C6 | XTP3 transactivated gene A protein | XTP3 transactivated protein A | XTP3-transactivated gene A protein

rp188369-10μg

10μg

无载体

≥90%(SDS-PAGE)

DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. DCTPP1 also hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). DCTPP1 does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP. It may protect DNA or RNA against the incorporation of non-canonical nucleotide triphosphates. DCTPP1 may also protect cells against inappropriate methylation of CpG islands by DNA methyltransferases.

重组表达

19.5 kDa

N-His

19.1 kDa, under reducing conditions; 20.0 & 37.1 kDa, under non-reducing conditions

E. coli Accession #: Q9H773 | E. coli

<1.0 EU/μg

人(Human)

2-170 aa

MHHHHHHSVAGGEIRGDTGGEDTAAPGRFSFSPEPTLEDIRRLHAEFAAERDWEQFHQPRNLLLALVGEVGELAELFQWKTDGEPGPQGWSPRERAALQEELSDVLIYLVALAARCRVDLPLAVLSKMDINRRRYPAHLARSSSRKYTELPHGAISEDQAVGPADIPCDSTGQTST​

No

Yes