Recombinant Human A2LD1 Protein

重组人A2LD1蛋白 | 重组人γ-谷氨酰胺环转移酶蛋白

AIG2-like domain-containing protein 1 | Gamma-glutamylamine cyclotransferase | Gamma-glutamylaminecyclotransferase | GGACT | GGACT_HUMAN

rp188397-10μg

10μg

无载体

≥95%(SDS-PAGE)

Gamma-glutamylaminecyclotransferase (A2LD1) is an enzyme which converts gamma-glutamylamines to free amines and 5-oxoproline. A2LD1 demonstrates high activity toward gamma-glutamyl-epsilon-lysine, derived from the breakdown of fibrin and other proteins cross-linked by transglutaminases. A2LD1 assists in the proteolytic degradation of crosslinked fibrin by breaking down isodipeptide L-gamma-glutamyl-L-epsilon-lysine, which is a byproduct of fibrin degradation. The reaction catalyzed by the A2LD1 produces 5-oxo-L-proline and a free alkylamine. Contributes to degradation of proteins cross-linked by transglutaminases by degrading the cross-link between a lysine and a glutamic acid residue. Catalyzes the formation of 5-oxo-L-proline from L-gamma-glutamyl-L-epsilon-lysine. Inactive with L-gamma-glutamyl-alpha-amino acid substrates such as L-gamma-glutamyl-L-alpha-cysteine and L-gamma-glutamyl-L-alpha-alanine.

重组表达

18.2 kDa

N-His

16.2 kDa, under reducing conditions; 16.2 kDa, under non-reducing conditions.

E. coli Accession #: Q9BVM4 | E. coli

<1.0 EU/μg

人(Human)

2-153 aa

MHHHHHHALVFVYGTLKRGQPNHRVLRDGAHGSAAFRARGRTLEPYPLVIAGEHNIPWLLHLPGSGRLVEGEVYAVDERMLRFLDDFESCPALYQRTVLRVQLLEDRAPGAEEPPAPTAVQCFVYSRATFPPEWAQLPHHDSYDSEGPHGLRYNPRENR​

No

Yes