Recombinant Human GPx-7 Protein

重组人GPx-7蛋白 | 重组人谷胱甘肽过氧化物酶 7蛋白

CL683 | FLJ14777 | Glutathione peroxidase 7 | GPx-7 | GPX6 | GPX7 | GPX7_HUMAN | GSHPx-7 | NPGPx

rp188401-10μg

10μg

无载体

≥90%(SDS-PAGE)

GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to differ by overlapping exons with different boundaries. GPX7 is an enzyme. It has molecular functions (glutathione peroxidase activity, oxidoreductase activity) and to localize in various compartments (extracellular space, extracellular region). GPX7 gene has been proposed to participate in pathways (Arachidonic acid metabolism, Glutathione metabolism), and processes (oxidation-reduction, response to oxidative stress). GPX7 modulates the bone turnover after ovariectomy in rats, it does not compensate for the action of estrogen after ovariectomy in rats. It has been shown that three mAbs (GPX7, GPX22, and GPZ35) inhibit IL-6-mediated biological responses such as Ig production in a human B cell line and proliferative responses of a human Lennert's lymphoma-derived T cell line, a human myeloma cell line, and a mouse pro-B cell line-derived transfectant expressing human gp130.

重组表达

20.0 kDa

N-His

20.5 kDa, under reducing conditions; 20.8 kDa, under non-reducing conditions.

E. coli Accession #: Q96SL4 | E. coli

<1.0 EU/μg

人(Human)

20-187 aa

MHHHHHHQQEQDFYDFKAVNIRGKLVSLEKYRGSVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEIESFARRTYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGKEPTWNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL​

No

Yes