Recombinant Human Glutathione Synthetase Protein

重组人Glutathione Synthetase蛋白 | 重组人谷胱甘肽合成酶蛋白

Glutathione Synthetase | GSH Synthetase | GSH-S | Glutathione Synthase | GSS

rp188403-10μg

10μg

无载体

≥95%(SDS-PAGE)

Catalyzes the production of glutathione from gamma-glutamylcysteine and glycine in an ATP-dependent manner (PubMed:7646467, PubMed:9215686). Glutathione (gamma-glutamylcysteinylglycine, GSH) is the most abundant intracellular thiol in living aerobic cells and is required for numerous processes including the protection of cells against oxidative damage, amino acid transport, the detoxification of foreign compounds, the maintenance of protein sulfhydryl groups in a reduced state and acts as a cofactor for a number of enzymes (PubMed:10369661). Participates in ophthalmate biosynthesis in hepatocytes (By similarity).

Immobilized Recombinant Human Glutathione Synthetase Protein (rp188403) at 1.0 μg/mL can bind Recombinant Glutathione Synthetase Antibody (Ab105758) with the EC50 of 7.1 ng/mL.

重组表达

53.2 kDa

C-His

49.6 kDa, under reducing conditions; 49.6 & 49.8 kDa, under non-reducing conditions.

E. coli Accession #: P48637 | E. coli

<1.0 EU/μg

人(Human)

1-474 aa

MATNWGSLLQDKQQLEELARQAVDRALAEGVLLRTSQEPTSSEVVSYAPFTLFPSLVPSALLEQAYAVQMDFNLLVDAVSQNAAFLEQTLSSTIKQDDFTARLFDIHKQVLKEGIAQTVFLGLNRSDYMFQRSADGSPALKQIEINTISASFGGLASRTPAVHRHVLSVLSKTKEAGKILSNNPSKGLALGIAKAWELYGSPNALVLLIAQEKERNIFDQRAIENELLARNIHVIRRTFEDISEKGSLDQDRRLFVDGQEIAVVYFRDGYMPRQYSLQNWEARLLLERSHAAKCPDIATQLAGTKKVQQELSRPGMLEMLLPGQPEAVARLRATFAGLYSLDVGEEGDQAIAEALAAPSRFVLKPQREGGGNNLYGEEMVQALKQLKDSEERASYILMEKIEPEPFENCLLRPGSPARVVQCISELGIFGVYVRQEKTLVMNKHVGHLLRTKAIEHADGGVAAGVAVLDNPYPVHHHHHH

No

Yes