Recombinant Human Peroxiredoxin 3/PRDX3 Protein

重组人Peroxiredoxin 3/PRDX3蛋白 | 重组人过氧化物酶3蛋白

Antioxidant protein 1 | AOP 1 | AOP-1 | AOP1 | HBC189 | MER5 | MGC104387 | MGC24293 | Mitochondrial | peroxiredoxin 3 | Peroxiredoxin III | Peroxiredoxin-3 | PRDX3 | PRDX3_HUMAN | PRO1748 | Protein MER5 homolog | PRX III | Prx-III | PRX3 | SP 22 | SP-22 |

rp188413-10μg

10μg

无载体

≥90%(SDS-PAGE)

Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides (PubMed:17707404, PubMed:29438714, PubMed:33889951, PubMed:7733872). Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol (PubMed:12492477). Required for the maintenance of physical strength (By similarity). Post-translational: Phosphorylated by LRRK2; phosphorylation reduces perodixase activity. The enzyme can be inactivated by further oxidation of the cysteine sulfenic acid (C(P)-SOH) to sulphinic acid (C(P)-SO2H) and sulphonic acid (C(P)-SO3H) instead of its condensation to a disulfide bond. S-palmitoylated.

Testing in progress

重组表达

35.2 kDa

N-His & SUMO

36.9 kDa, under reducing conditions; 36.0 & 73.8 & 89.4 kDa, under non-reducing conditions.

E. coli Accession #: P30048 | E. coli

<1.0 EU/μg

人(Human)

63-256 aa

MGSSHHHHHHSSGLVPRGSHMASMSDSEVNQEAKPEVKPEVKPETHINLKVSDGSSEIFFKIKKTTPLRRLMEAFAKRQGKEMDSLRFLYDGIRIQADQTPEDLDMEDNDIIEAHREQIGGPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQ

No

Yes