Recombinant Human BTF3 Protein

重组人BTF3蛋白 | 重组人基本转录因子3蛋白

Basic transcription factor 3 | BETA NAC | BTF 3 | btf3 | BTF3_HUMAN | BTF3a | BTF3b | NACB | Nascent polypeptide associated complex beta polypeptide | RNA polymerase B transcription factor 3 | Transcription factor BTF3

rp189279-10μg

10μg

无载体

≥90%(SDS-PAGE)

When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. Post-translational: Phosphorylated upon DNA damage, probably by ATM or ATR.

重组表达

23.0 kDa

N-His

26.5 kDa, under reducing conditions; 26.5 & 54.1 kDa, under non-reducing conditions.

E. coli Accession #: P20290 | E. coli

<1.0 EU/μg

人(Human)

2-206 aa

MHHHHHHRRTGAPAQADSRGRGRARGGCPGGEATLSQPPPRGGTRGQEPQMKETIMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTATADDKKLQFSLKKLGVNNISGIEEVNMFTNQGTVIHFNNPKVQASLAANTFTITGHAETKQLTEMLPSILNQLGADSLTSLRRLAEALPKQSVDGKAPLATGEDDDDEVPDLVENFDEASKNEAN

No

Yes