Recombinant Human EIF3S1/EIF3J Protein

重组人EIF3S1/EIF3J蛋白 | 重组人真核翻译起始因子3亚基J蛋白

eIF 3 alpha | eIF-3-alpha | eIF3 alpha | eIF3 p35 | eIF3j | EIF3J_HUMAN | EIF3S 1 | EIF3S1 | Eukaryotic translation initiation factor 3 subunit 1 | Eukaryotic translation initiation factor 3 subunit J | Eukaryotic translation initiation factor 3, subunit

rp192076-10μg

10μg

无载体

≥90%(SDS-PAGE)

Eukaryotic translation initiation factor 3 subunit J (EIF3J) is a member of the EIF-3 subunit J family. EIF3 has a crucial role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to produce the 40S initiation complex. EIF3J binds to the aminoacyl (A) site and mRNA access channel of the 40S subunit, setting EIF3J directly in the ribosomal decoding center. In addition, EIF3J interacts with eIF1A and reduces 40S subunit affinity for mRNA. An elevated affinity for mRNA is restored upon enlistment of initiator tRNA, despite the fact EIF3J remains in the mRNA-binding cleft in the presence of tRNA. Post-translational: Phosphorylated. Phosphorylation is enhanced upon serum stimulation.

Immobilized Recombinant Human EIF3S1/EIF3J Protein (rp192076) at 1.0 μg/mL can bind EIF3S1/EIF3J Antibody (Ab101341) with the EC50 of 72.7 ng/mL.

重组表达

22.7 kDa

N-His

26.6 kDa, under reducing conditions; 26.6 kDa, under non-reducing conditions.

E. coli Accession #: O75822 | E. coli

<1.0 EU/μg

人(Human)

70-258 aa

MHHHHHHKISEKKKIAEKIKEKERQQKKRQEEIKKRLEEPEEPKVLTPEEQLADKLRLKKLQEESDLELAKETFGVNNAVYGIDAMNPSSRDDFTEFGKLLKDKITQYEKSLYYASFLEVLVRDVCISLEIDDLKKITNSLTVLCSEKQKQEKQSKAKKKKKGVVPGGGLKATMKDDLADYGGYDGGYVQDYEDFM

No

Yes