Recombinant Human GNB1 Protein

重组人GNB1蛋白 | 重组人鸟嘌呤核苷酸结合蛋白 G(I)/G(S)/G(T) 亚基 beta-1 蛋白

Beta subunit signal transducing proteins GS/GI | G protein beta 1 subunit | GBB1 | GBB1_HUMAN | gnb1 | Guanine nucleotide binding protein (G protein) beta polypeptide 1 | Guanine nucleotide binding protein beta 1 subunit | Guanine nucleotide-binding prote

rp192116-10μg

10μg

无载体

≥80%(SDS-PAGE)

Heterotrimeric guanine nucleotide-binding proteins (G proteins) which integrate signals between receptors and effector proteins, are comprised of an alpha, a beta and a gamma subunit. The alpha, beta and gamma subunits are encoded by families of related genes. GNB1 encodes a beta subunit. Beta subunits are vital regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. G proteins are involved as a modulator or transducer in numerous transmembrane signaling systems. The beta and gamma chains are necessary for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. Post-translational: Phosphorylation at His-266 by NDKB contributes to G protein activation by increasing the high energetic phosphate transfer onto GDP.

Immobilized Recombinant Human GNB1 Protein (rp192116) at 1.0 μg/mL can bind GNB1 Antibody (Ab105938) with the EC50 of 16.9 ng/mL.

重组表达

38.2 kDa

N-His

34.7 kDa, under reducing conditions; 33.9 kDa, under non-reducing conditions.

E. coli Accession #: P62873 | E. coli

<1.0 EU/μg

人(Human)

2-340 aa

MHHHHHHSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN

No

Yes