Recombinant Human KCNIP3 Protein

重组人KCNIP3蛋白 | 重组人钾通道相互作用蛋白3

4933407H12Rik | A type potassium channel modulatory protein 3 | A-type potassium channel modulatory protein 3 | AI413860 | Calsenilin | CSEN | CSEN_HUMAN | DRE antagonist modulator | DRE-antagonist modulator | DREAM | EF hand transcription factor | KCHIP

rp192130-10μg

10μg

无载体

≥95%(SDS-PAGE)

KCNIP3 belongs to a family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. KCNIP family members are small calcium binding proteins containing EF-hand-like domains. KCNIP3 also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Mutations in the presenilin genes are implicated in Alzheimer's disease. Post-translational: Palmitoylated. Palmitoylation enhances association with the plasma membrane (By similarity). Proteolytically cleaved by caspase-3. Phosphorylation at Ser-63 inhibits cleavage by CASP3.

重组表达

30.0 kDa

N-His

29.1 kDa, under reducing conditions; 29.1 kDa, under non-reducing conditions.

E. coli Accession #: Q9Y2W7 | E. coli

<1.0 EU/μg

人(Human)

2-256 aa

MHHHHHHQPAKEVTKASDGSLLGDLGHTPLSKKEGIKWQRPRLSRQALMRCCLVKWILSSTAPQGSDSSDSELELSTVRHQPEGLDQLQAQTKFTKKELQSLYRGFKNECPTGLVDEDTFKLIYAQFFPQGDATTYAHFLFNAFDADGNGAIHFEDFVVGLSILLRGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFLEACQKDENIMSSMQLFENVI

No

Yes