Recombinant Human Serpin B3/SSCA1 Protein

重组人Serpin B3/SSCA1蛋白 | 重组人丝氨酸蛋白酶抑制剂B3

HsT1196 | Protein T4-A | SCC | SCCA | SCCA1 | SCCA1SCCA-1 | SCCA-PD | serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 3 | Serpin B3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | Squamous cell carcinoma antigen 1 | T4

rp214464-10μg

10μg

无载体

≥90%(SDS-PAGE)

Serpin B3, also known as squamous cell carcinoma antigen-1 (SCCA-1), is a member of the serpin superfamily of serine protease inhibitors. Serpins primarily inhibit serine proteases and some are known to inhibit caspases and papain-like cysteine proteases. Serpin B3 belongs to the subgroup ovalbumin-related serpins which are involved in the regulation of apoptosis, inflammation, angiogenesis and embryogenesis. Serpin B3 was initially isolated from human cervical squamous cell tissue. It is a tumor marker for squamous cell carcinomas in various areas including the cervix, head, neck and lung. Unlike typical serpins, Serpin B3 shows inhibitory activity against papain-like lysosomal cysteine proteases Cathepsin K, L, and S, while lacking inhibitory activity against serine proteases.

重组表达

45.4 kDa

N-His

42.9 kDa, under reducing conditions; 42.9 kDa, under non-reducing conditions.

E. coli Accession #: P29508 | E. coli

<1.0 EU/μg

人(Human)

2-390 aa

MHHHHHHNSLSEANTKFMFDLFQQFRKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLEDVQAKVLEIPYKGKDLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRETRVDLHLPRFKVEESYDLKDTLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTSTNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP

No

Yes