Recombinant Human 14-3-3 tau/theta Protein

重组人14-3-3 tau/theta蛋白 | 重组人14-3-3蛋白tau/theta亚型

14-3-3 protein T cell | 14-3-3 protein T-cell | 14-3-3 protein tau | 14-3-3 protein theta | 1433T_HUMAN | IC5 | Protein HS1 | Protein tau | Ywhaq | YWHAQ tyrosine 3 monooxygenase/tryptophan 5-monooxygenase activation protein | theta polypeptide

rp220396-10μg

10μg

无载体

≥90%(SDS-PAGE)

The 14-3-3 family of proteins plays a key regulatory role in signal transduction, checkpoint control, apoptotic and nutrient-sensing pathways. 14-3-3 proteins are highly conserved and ubiquitously expressed. There are at least seven isoforms, beta, gamma, epsilon,sigma, zeta, tau and eta that have been identified in mammals. The 14-3-3 tau, a subtype of the 14-3-3 family of proteins, was found in T Cells, brain and testes. This 14-3-3 tau is upregulated in patients with amyotrophic lateral sclerosis. Recombinant human YWHAQ was expressed in E.coli and purified by using conventional chromatography techniques. Post-translational: Ser-232 is probably phosphorylated by CK1.

重组表达

28.6 kDa

N-His

27.4 kDa, under reducing conditions; 20.0-26.2 & 50.0 kDa, under non-reducing conditions.

E. coli Accession #: P27348 | E. coli

<1.0 EU/μg

人(Human)

2-245 aa

MHHHHHHEKTELIQKAKLAEQAERYDDMATCMKAVTEQGAELSNEERNLLSVAYKNVVGGRRSAWRVISSIEQKTDTSDKKLQLIKDYREKVESELRSICTTVLELLDKYLIANATNPESKVFYLKMKGDYFRYLAEVACGDDRKQTIDNSQGAYQEAFDISKKEMQPTHPIRLGLALNFSVFYYEILNNPELACTLAKTAFDEAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDSAGEECDAAEGAEN

No

Yes